How Is BHRT Different From Traditional HRT? Traditional hormone replacement therapy (HRT) uses synthetic hormones that raises your blood levels to supra-physiologic levels. This in-turn sets off a natural negative feedback by the body which further depresses the body’s own production of the hormones. Since these hormones are synthetic, there are many potentially unwanted side-effects and possible dangers that have scared off too many patients from seeking treatment. BHRT at The Youth Fountain uses hormones that are identical to what your body makes. These hormones can be applied directly to the skin in the form of a cream. The levels can be controlled better than their synthetic counterparts. This allows for a more physiologic and natural replacement that is safer than traditional HRT.